Department of Imaging Physics, Delft University of Technology

Welcome to the KaLKMaNLaB for optical tomography

We develop novel optical instrumentation to look inside objects. We focus on various application areas where optical tomography plays a key role. Our instrumentation development tools are numerical imaging system simulation, optical design, and laboratory experimental validation. We keep a close eye on potential applications with our industrial and research partners.

3D Tomography

Sharper, faster, larger

Both in hardware and in software we focus on creating sharper images, imaging at a faster rate, and imaging larger volumes. We do this by improving existing techniques such as optical coherence tomography, optical projection tomography, and phase tomography, but we also develop novel imaging geometries that have enhanced imaging performance.

Quantitative Optical Imaging

Getting the numbers right

We do not only focus on making nice images, but also in the extraction of physical parameters from the optical data. We keep a keen eye on developing imaging based sensor technology for industrial applications.

Large scale 3D optical diffraction tomography imaging of a zebrafish larva.


January 16, 2024
Paper published on "Experiment and theory of the complex refractive index of dense colloidal media".

December 6, 2023
PhD defence Jos de Wit "Microscopic 3D plant imaging with high-resolution optical coherence tomography".

October 9, 2023
Presenting our work on "In vivo 3D visualization of plant-pathogen interaction using dynamic optical coherence tomography" at NWO Biophysics 2023.

September 26, 2023
Presenting our work on "Basics and applications of optical coherence tomography" at TUe integrated photonics retreat in Deurne.